KMID : 0352719930170020127
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Journal of Ginseng Research 1993 Volume.17 No. 2 p.127 ~ p.130
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Inhibition of Serotonin Release by Lipophilic Fraction From Korean Red Ginseng
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À̸¸Èñ
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Abstract
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Lipophilic fractions (LF) from Panax ginseng C. A. Meyer strongly inhibited human platelet aggregations induced by thrombin, When platelets were prelabeled with 5-Hydroxy[G-3H]-tryptamine (serotonin) and then stimulated by thrombin. LF inhibited
the
release of serotonin in a dose-dependent manner. From this result, we suggest that LF have antiplatelet and antimigraine functions by inhibiting the release of serotonin
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